All studies

pregnancy photo_spacer-01.jpgCarelon Research researchers develop pregnancy algorithm critical for maternal and infant health outcomes research



This algorithm will assist Carelon Research and Elevance Health in assessing drug safety during pregnancy, developing best practices and protocols, and improving services and costs through refined policies.

Enterprise Analytics Hub domain(s): maternity

Summary

Background
Elevance Health insures one in ten babies born in the U.S. However, there is no unified approach for identifying pregnant members and their babies in studying maternal and infant health outcomes using administrative claims data. This presented the need for an in-house algorithm that utilizes the newly released ICD-10 codes to efficiently identify pregnancies, estimate gestational age, and determine the start of the pregnancy for population management and research.

Methods
 We reviewed the literature, health plan guidelines, and currently used coding system, consulted with medical experts, and created a ranking system based on code specificity of reporting end of pregnancy (EOP) events. A different criterion for birth events (equal to or greater than 20 weeks) vs. early pregnancy loss (less than 20 weeks) was developed. A similar method for gestational age estimation and the start of pregnancy determination was followed to create a hierarchical approach that favors specific codes based on each code specificity or trimesters. In addition, this algorithm can capture multiple pregnancies in the same woman.


Results
After much testing, Carelon Research adopted this algorithm as a standard process in all maternity research. Other Elevance Health researchers and decision makers may leverage the algorithm.

Pregnancy Figure 1.jpg
Pregnancy Figure 2.jpg
Key takeaways
This presents several opportunities for Elevance Health:

  • Improve efficiency in conducting pregnancy safety studies and research
  • Identify current clinical practices and integration of benefits to improve services and costs through refined policies

Publications

Jamal-Allial A, He X, Avula R, Dinh J, Lanes S. Developing Methodology to Estimate Gestational Age Using Administrative Claims. Pharmacoepidem Dr S, 2020. 29(S3): p. 684. (abstract #4957)

Jamal-Allial A, Dinh J, Vojjala S, Lanes S. Implementation of ICD‐10‐CM Z3A% codes in real‐world evidence studies of pregnancy outcomes. Pharmacoepidem Dr S, 2019. 28(S2): p. 356. (abstract #741)

Carelon Research project team: Aziza Jamal-Allial, Ramya Avula, Kerrin Gallagher 



For more information on a specific study or to connect with the Actionable Insights Committee, contact us at [email protected].

This study was conducted by Carelon Research (formerly HealthCore, Inc.), a subsidiary of Elevance Health. Dissemination and sharing of the Newsletter is limited to Elevance Health and its subsidiaries and included findings and implications are for Elevance Health and its affiliates’ internal use only.


Ready to get started? Sign up now!

Lorem ipsum dolor sit amet

2-Col, Right Image

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut.

Lorem ipsum dolor sit amet, consectetur adipisicing, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut. Ut ad minim veniam.

Vestibulum ante ipsum primis in faucibus orci luctus etel ultrices posuere cubilia Curae.

2-Col, Left Image

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut.

  • Many addon features
  • Fully responsive & adaptive
  • SEO optimized
  • Attractive with a modern touch
  • Full Support

Ut Enim Minima

Sed ut perspiciatis unde omnis iste natus error sit voluptatem!

Quis Autem Vel

Nemo enim ipsam voluptatem quia voluptas sit odit aut fugit!

Quo Voluptas

Ut enim ad minima veniam, quis nostrum exercitationem ullam!

Real-world treatment patterns associated with new antidiabetic drug provide insights on clinician efforts to optimize type 2 diabetes (T2D) therapy

Once-weekly semaglutide (Ozempic; sema OW) is being initiated further down the T2D treatment pathway...

Real-world evidence supports NCCN guidelines recommending against first-line use of chemoimmunotherapy (CIT) in high-risk CLL/SLL patients

First-line use of CIT for patients with genetic abnormalities in CLL/SLL, a cancer of the blood and bone marrow...

Consectetur adipiscing elit...

Joanna C.

"Et harum quidem rerum facilis est et expedita distinctio!"

Stanley T.

"Nam libero tempore, cum soluta nobis est eligendi."

Danielle W.

"Temporibus autem quibusdam et aut officiis debitis!"

Teams at Carelon Research

The clinical research team at Carelon Research coordinates and conducts a broad range of clinical trials and registries – from small studies focused on rare and orphan diseases to large studies of complex and chronic conditions. We work with projects across the research spectrum, including life sciences, biotech, medical device, diagnostics, the government (National Institutes of Health, CDC, etc.) and academic institutions. For more information, visit our clinical research page.
The business development and marketing and communications experts at Carelon Research work with external clients and internal subject matter experts to develop a variety of research projects and disseminate results via conferences and digital marketing platforms including email and social media.
The HEOR team at Carelon Research develops study designs, translates value stories, and facilitates payer collaborations. Our researchers generate evidence of the real-world value of biomedical products and translate that evidence into actionable information for stakeholders. For more information, visit our health economics and outcomes research page.
The research operations team at Carelon Research focuses on improving the efficiency, effectiveness, and profitability of business performance and operations. The team includes the project and program management team, operational leaders focused on ensuring program/project goals are met according to plan, schedule, and scope; the data management team, specializing in the application of techniques to access, collect, integrate, cleanse, govern, store, and prepare data for analytics and ensures the body of data at Carelon Research is accurate and consistent, accessible, and properly secured; and the data analytics team of biostatisticians and analysts provide advanced analytic expertise and programming capabilities to lead and support the company’s scientific portfolio of database and clinical research.
The safety & epidemiology research team at Carelon Research uncovers vital evidence on the utilization, safety, and effectiveness of biopharmaceuticals and devices in large, real-world patient populations. Our researchers provide a broad range of expertise and operational experience to the timely and accurate execution of epidemiologic studies in the pre- and post-marketing settings. For more information, visit our safety and epidemiology research page.